HIGHLIGHTS
- who: Fiorella Scagnoli and colleagues from the Department, Sapienza University, Rome, Italy have published the article: A New Insight into MYC Action: Control of RNA Polymerase II Methylation and Transcription Termination, in the Journal: Biomedicines 2023, 11, 412. of 13/Dec/2022
- what: The authors show that overexpression strongly increases R1810me2s while Omomyc an shRNA or PRMT5 inhibitor and siRNA counteract this phenomenon. Following the previous papers, showing a mutual functional interaction between MYC and PRMT5 , in this work the authors showed, for the first time, that MYC may have a role in transcript termination . . .
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