A new lc-ms assay for the quantitative analysis of vitamin k metabolites in human urine[s]

HIGHLIGHTS

• who: McDonald Matthew G. from the DepartmentsUniversity of, Tokyo, Japan have published the paper: A new LC-MS assay for the quantitative analysis of vitamin K metabolites in human urine[S], in the Journal: (JOURNAL)
• what: The authors describe the first LC-MS/MS assay for the accurate and precise quantitation of K acids I and II in human urine and report the identification of a new VK metabolite, MK1 -COOH (Fig 1). The authors propose that the m/z 197/195 fragment ions may result from a mechanism involving an initial side-chain double . . .
  

   

  

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