A new manganese superoxide dismutase mimetic improves oxaliplatin-induced neuropathy and global tolerance in mice

HIGHLIGHTS

• who: Caroline Prieux-Klotz and colleagues from the Institut Cochin, INSERM U , CNRS UMR, Universitu00e9 de Paris, Paris, France Laboratoire des Biomolu00e9cules, LBM, Du00e9partement de Chimie, Ecole Normale Supu00e9rieure, PSL University have published the research: A New Manganese Superoxide Dismutase Mimetic Improves Oxaliplatin-Induced Neuropathy and Global Tolerance in Mice, in the Journal: (JOURNAL)
• how: The authors designed and synthesized the first Pt(IV) complexes as covalent conjugates between oxaliplatin and MnSOD mimics derived from complex Mn1 (MAG) to evaluate them for their antitumoral activity and effect on oxaliplatin-induced peripheral neuropathy. This result can . . .
  

   

  

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