A new mode of regulation of n-type inactivation in a caenorhabditis elegans voltage-gated potassium channel*

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  • who: Shi-Qing Cai from the Shi-Qing Cai and Federico Sesti, From the Department of Physiology and Biophysics, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, Piscataway, New Jersey , type inactivation in voltage-gated Kⴙ (Kv) channels is a widespread means to modulate neuronal excitability and signalingHere we have shown a novel mechanism of, type inactivation in a Caenorhabditis elegans Kv channel. The, terminal sequence of , contains a domain of , amino acids that resembles the inactivation ball in, type channels, which is preceded by a domain of eighteen amino acids. Wild . . .

     

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