A new optimized version of a colorectal cancer-targeted immunotoxin based on a non-immunogenic variant of the ribotoxin -sarcin

HIGHLIGHTS

  • who: Javier Narbona and colleagues from the Department of Biochemistry and Molecular Biology, Faculty of Chemical Sciences, Complutense University, Madrid, Spain have published the research: A New Optimized Version of a Colorectal Cancer-Targeted Immunotoxin Based on a Non-Immunogenic Variant of the Ribotoxin -Sarcin, in the Journal: Cancers 2023, x of 13/01/2023
  • what: The authors designed two different variants of non-immunogenic immunotoxins (IMTXA33u03b1SDI and IMTXA33furu03b1SDI) on deimmunized variant of the The work described herein represents a step forward in the design of potential therapeutic immunotoxins based on a non-immunogenic variant . . .

     

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