HIGHLIGHTS
- who: COPYRIGHT and collaborators from the Nihon University, Japan have published the article: A new strategy for osteoarthritis therapy: Inhibition of glycolysis, in the Journal: (JOURNAL)
- what: The aims of modern OA treatment are to reduce pain, improve or maintain joint function, increase joint strength, and prevent further OA development (Xu et_al, 2019).
- how: This paper discussed the rate-limiting enzymes and metabolites involved in chondrocyte glycolysis that may have significant breakthroughs in OA treatment. The mRNA sequencing results showed that IL-1u03b2 induction significantly increased the expression of genes involved in glycolysis . . .
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