A new sugar for an old phage: a c-di-gmp-dependent polysaccharide pathway sensitizes escherichia coli for bacteriophage infection

HIGHLIGHTS

  • who: Benjamin Sellner et al. from the University of, Molecular Systems Basel, Basel, Switzerland have published the Article: A New Sugar for an Old Phage: a c-di-GMP-Dependent Polysaccharide Pathway Sensitizes Escherichia coli for Bacteriophage Infection, in the Journal: (JOURNAL) of 05/01/2022
  • what: The authors show that bacteriophage N4 exploits a novel surface glycan (NGR) as a receptor to infect its host Escherichia coli. The authors demonstrate that this process is regulated by the second messenger c-di-GMP and that N4 infection is specifically stimulated by the diguanylate cyclase while . . .

     

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