HIGHLIGHTS
- who: Subject Category Post-translational Modifications and collaborators from the University of Dundee have published the research work: A nonu2010canonical scaffoldu2010type E3 ligase complex mediates protein UFMylation, in the Journal: (JOURNAL)
- what: The authors show that UFL1/UFBP1 utilizes ligase mechanism that activates the UFM1-conjugating enzyme UFC1 for aminolysis. The authors characterize second adaptor protein CDK5RAP3 that binds to and forms an integral part of the ligase complex. To analyze how the E2 UFC1 works together with the E3 ligase UFL1 to transfer UFM1, the authors aimed to reconstitute UFMylation reactions using purified components . . .
If you want to have access to all the content you need to log in!
Thanks :)
If you don't have an account, you can create one here.