A nonpeptide oxytocin receptor agonist for a durable relief of inflammatory pain

HIGHLIGHTS

  • who: Louis Hilfiger from the CentreScientifique and University of have published the Article: A Nonpeptide Oxytocin Receptor Agonist for a Durable Relief of Inflammatory Pain, in the Journal: Scientific Reports Scientific Reports
  • what: The authors report that a single intraperitoneal administration of LIT-001 in a rat model induces a long-lasting reduction in inflammatory pain-induced hyperalgesia symptoms, paving the way to an original drug development strategy for pain treatment. The authors show that LIT-001, a non-peptidergic specific agonist for OTR, exerts a significant long-lasting (>5 h) anti-hyperalgesic effect on . . .

     

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