A notch1/lsd1/bmp2 co-regulatory network mediated by mir-137 negatively regulates osteogenesis of human adipose-derived stem cells

HIGHLIGHTS

  • who: Cong Fan from the Department of General Dentistry II, Peking University School and Hospital of Stomatology, Beijing, China have published the article: A NOTCH1/LSD1/BMP2 co-regulatory network mediated by miR-137 negatively regulates osteogenesis of human adipose-derived stem cells, in the Journal: (JOURNAL)
  • what: The study provided a relatively sive rationale for the negative modulation during the hASC differentiation towards lineage and established a co-regulatory NOTCH1/LSD1/BMP2 to elucidate the comprehenof miR-137 osteoblastic network of underlying mechanisms, which is of substantial importance for potential targeted therapy of bone . . .

     

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