A novel anti-membrane cd30 single-chain variable fragment discovered from the human phage library: a potential targeted immunotherapy

HIGHLIGHTS

  • who: Thanida Chanpong and collaborators from the DuPont Hospital for Children, UNITED STATES and Technology Development Agency, Thailand , Graduate Program in Molecular Medicine, Faculty of Science, Mahidol University, Bangkok, Thailand have published the article: A novel anti-membrane CD30 single-chain variable fragment discovered from the human phage library: A potential targeted immunotherapy, in the Journal: PLOS ONE of 28/Dec/2022
  • what: To address the issue of the sCD30-neutralizing, reduce HAMA toxicities, and enhance CD30-targeted immunotherapy, this study aimed to discover human scFvs that recognize mCD30 epitopes (mCD30-scFvs).
  • how . . .

     

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