A novel anti-tnf-α drug ozoralizumab rapidly distributes to inflamed joint tissues in a mouse model of collagen induced arthritis

HIGHLIGHTS

• who: Shohei Oyama from the DepartmentOsaka University have published the Article: A novel anti-TNF-u03b1 drug ozoralizumab rapidly distributes to inflamed joint tissues in a mouse model of collagen induced arthritis, in the Journal: Scientific Reports Scientific Reports
• what: The authors administered approximately four times the dose, on a molar basis, of ozoralizumab-Alexa 680 as compared with that of adalimumab-Alexa 680.
• how: These results indicated that labeling with Alexa 680 exerted limited effect on the binding affinity of ozoralizumab for MSA. All methods were carried out following relevant guidelines and . . .
  

   

  

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