A novel class of hiv-1 inhibitors targeting the vpr-induced g2-arrest in macrophages by new yeast- and cell-based high-throughput screening

HIGHLIGHTS

• who: Hirotaka Sato and collaborators from the Division of Hematology and Rheumatology, Department of Medicine, Nihon University School of Medicine, Shimotsuga, Tochigi, Japan have published the Article: A Novel Class of HIV-1 Inhibitors Targeting the Vpr-Induced G2-Arrest in Macrophages by New Yeast- and Cell-Based High-Throughput Screening, in the Journal: Viruses 2022, 14, 1321. of /2022/
• what: The authors designed yeast and mammalian cell-based its derivatives .
• how: The authors employed previously described Vpr-expressing yeast as a tool for screening the inhibitors of the Vpr-mediated G2/M . . .
  

   

  

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