A novel classification model for lower-grade glioma patients based on pyroptosis-related genes

HIGHLIGHTS

  • who: Yusheng Shen and collaborators from the Department of Neurosurgery, The First Affiliated Hospital of Xinjiang Medical University have published the article: A Novel Classification Model for Lower-Grade Glioma Patients Based on Pyroptosis-Related Genes, in the Journal: (JOURNAL) of 19/07/2021
  • what: In the validation cohort, this model had AUCs of 0.879 (1-year), 0.871 (3-year), and 0.672 (5-year) . The study demonstrated that pyroptosis in myeloid cells shapes an inflammatory and immunesuppressive microenvironment, thus promoting the development of lower-grade glioma, which is consistent with previous studies . . .

     

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