A novel dna damage repair gene-related prognostic model for evaluating the prognosis and tumor microenvironment infiltration of esophageal squamous cell carcinoma

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SUMMARY

    (ESCC) is the main histologic type of esophageal cancer. Distinguishing these tumor cells from normal cells can improve the treatment response of cancer. DDR gene (DDRG) mutations usually result in a high somatic mutation load in malignant cells, and these variations in turn trigger the production of tumor-specific neoantigens. Chae et_al found that a DDRG signature was predictive of patient prognosis in glioma cells. The authors found that the infiltration levels of naive CD4 T_cells, activated mast cells and monocytes were significantly higher in the low-risk group. Naive CD4 T_cells are a . . .

     

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