A novel evolutionary conserved mechanism of rna stability regulates synexpression of primordial germ cell-specific genes prior to the sex-determination stage in medaka

HIGHLIGHTS

• who: Amaury Herpin et al. from the INRA, Fish Physiology and Genomics, Rennes, France, University of Wuerzburg, Physiological have published the research: A novel evolutionary conserved mechanism of RNA stability regulates synexpression of primordial germ cell-specific genes prior to the sex-determination stage in medaka, in the Journal: (JOURNAL)
• what: The authors show here that in medaka two RNA-binding proteins with antagonizing properties target this D3U-box promoting either RNA stabilization in germ cells or degradation in the soma. The authors show that the dmrt1 11-nucleotide cis-regulatory D3U-Box motif is . . .
  

   

  

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