A novel glucagon analog with an extended half-life, hm15136, normalizes glucose levels in rodent models of congenital hyperinsulinism

HIGHLIGHTS

• who: Yong Ho Heo from the College University, Heukseoku2011ro, Dongjaku2011gu, Seoul, Republic of Korea, have published the paper: A novel glucagon analog with an extended half-life, HM15136, normalizes glucose levels in rodent models of congenital hyperinsulinism, in the Journal: Scientific Reports Scientific Reports of 28/06/2022

SUMMARY

Compared to native glucagon, HM15136 showed markedly lower turbidity at both days 0 and 20 after addition to PBS, indicating that the solubility of HM15136 is much higher than that of the native glucagon (Fig 1C). The authors demonstrated that HM15136 shows dramatically increased . . .

 



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