A novel high-content immunofluorescence assay as a tool to identify at the single cell level γ-globin inducing compounds

HIGHLIGHTS

  • who: Marta Durlak and collaborators from the Scienze della Salute, Università degli studi di Milano-Bicocca, Monza, Italy have published the Article: A Novel High-Content Immunofluorescence Assay as a Tool to Identify at the Single Cell Level Γ-Globin Inducing Compounds, in the Journal: PLOS ONE | DOI:10.1371/journal.pone [0141083]. October 28, 2015 of /1371/
  • how: This result is particularly interesting as several metalloporphyrins have already been developed for clinical uses and could be tested (alone or in combination with other drugs) to improve pharmacological reactivation for the treatment of β-hemoglobinopathies.
 

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