A novel monoclonal antibody targeting cancer-specific plectin has potent antitumor activity in ovarian cancer

HIGHLIGHTS

  • who: Samantha M. Perez and collaborators from the Department of Biomedical Engineering, University of Virginia, Charlottesville, VA, USA have published the article: A Novel Monoclonal Antibody Targeting Cancer-Specific Plectin Has Potent Antitumor Activity in Ovarian Cancer, in the Journal: Cells 2021, 10, x FOR PEER REVIEW of 27/08/2021
  • what: The authors evaluate 1H110 s efficacy in treating CSP + OC. This study shows the therapeutic utility of targeting noncanonical cell surface proteins, opening the door to this class of proteins as novel therapeutic targets. The authors demonstrate that 1H11 elevates cellular ROS levels . . .

     

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