A novel platinum compound inhibits constitutive stat3 signaling and induces cell cycle arrest and apoptosis of malignant cells*

HIGHLIGHTS

• who: James Turkson from the (UNIVERSITY) have published the research: A Novel Platinum Compound Inhibits Constitutive Stat3 Signaling and Induces Cell Cycle Arrest and Apoptosis of Malignant Cells*, in the Journal: (JOURNAL) of September/23,/2005
• what: The authors demonstrate that a new platinum (IV) compound, IS3 295, selected from the NCI diversity set (NSC 295558) is another novel Stat3 inhibitor. Altogether, the authors provide evidence for direct inhibition of Stat3 and its biological activity by a novel platinum (IV) complex.
• how: In control studies the authors evaluated the effect of IS3 295 . . .
  

   

  

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