A novel rgd-4c-saporin conjugate inhibits tumor growth in mouse models of bladder cancer

HIGHLIGHTS

  • who: Stefania Zuppone from the Urological Research Institute, Division of Experimental Oncology, IRCCS San Raffaele Scientific Institute, Milano, Italy, Central University of Punjab, India have published the paper: A Novel RGD-4C-Saporin Conjugate Inhibits Tumor Growth in Mouse Models of Bladder Cancer, in the Journal: (JOURNAL)
  • what: The authors show that the RGD-SAP conjugate can be easily produced in E.coli with no need of renaturation, and that this product can kill integrinexpressing cells more efficiently than a SAP variant lacking the RGD domain. The authors show that RGD-SAP can inhibit the . . .

     

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