A novel role for mitochondrial fission in macrophages: trained innate immunity induced by beta-glucan

HIGHLIGHTS

  • who: Anna Brichkina from the The group of Jun Yan from the University have published the paper: A novel role for mitochondrial fission in macrophages: trained innate immunity induced by beta-glucan, in the Journal: (JOURNAL) of 27/03/2023

SUMMARY

    Received A. Brichkina and H.-U. Simon They observed that WGP increased the production of TNF-α in lung interstitial macrophages and enhanced their phagocytic capacity and cytotoxicity to tumor cells. Interestingly, previously published pathways involved in inducing trained immunity, including the mTOR/HIF-1α or Nlrp3 inflammasome and IL-1β/IL-1R . . .

     

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