A novel small molecule, as1, reverses the negative hedonic valence of noxious stimuli

HIGHLIGHTS

  • who: Kali Esancy from the Department of Biological Structure, University of Washington, Seattle, USA have published the paper: A novel small molecule, AS1, reverses the negative hedonic valence of noxious stimuli, in the Journal: (JOURNAL)
  • what: Background is the primary reason people seek medical care with chronic affecting ~ 20% of people in the USA. F Velocity data for the experiments shown in E.
  • how: In a previously published study the authors developed a novel high-throughput temperature discrimination assay utilizing larval zebrafish that modeled acute and sensitized temperature aversion (Fig 1A) . Given such . . .

     

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