A novel stem cell model to study preeclampsia endothelial dysfunction

HIGHLIGHTS

• What: The aim of this study was to establish a replenishable patient-specific in vitro EC model to allow robust mechanistic studies to dissect endothelial in preeclampsia. Through this research, the authors aim to contribute to the development of improved diagnostic tools, targeted therapies, and preventive strategies that will significantly impact the management of PE and improve outcomes for both mothers and babies. The authors did not attempt to determine which circulating factors in the sera triggered the endothelial dysfunction, nor what accounted for the differential response by the different patient-derived ECs. This model provides the . . .
  

   

  

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