HIGHLIGHTS
SUMMARY
In terms of gene-editing, the variant Ripk2Asn104Asp in zebrafish augmented the innate immune_response and NF-kB pathway in early-onset osteoarthritis by CRISPR technique. In vivo imaging Following anesthesia, OCT imaging was obtained by a Micron IV retinal imaging microscope (Phoenix Research Laboratories, Pleasanton, CA) at 0 hpi (Blank control), 4 hpi, 12 hpi, 24 hpi, and 72 hpi of LPS. H and amp;E staining At 0 hpi, 4 hpi, 12 hpi, 24 hpi, 72 hpi, 5 days post injection (dpi) and 7dpi of LPS, zebrafish were anesthetized in 0.1% buffered . . .
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