A nuclear export signal in khnyn required for its antiviral activity evolved as zap emerged in tetrapods

HIGHLIGHTS

  • who: Maria J. Lista and collaborators from the Department of Infectious Diseases, London, United Kingdom have published the article: A Nuclear Export Signal in KHNYN Required for Its Antiviral Activity Evolved as ZAP Emerged in Tetrapods, in the Journal: (JOURNAL) of 26/01/2023
  • what: Since there is an experimentally determined structure for the CUBAN domain , and its role for KHNYN antiviral activity is not known, the authors focused on this domain.
  • how: Because interacts with and is required for its antiviral activity against retroviruses the authors conducted an evolutionary analysis to determine . . .

     

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