A pathophysiological model of non-alcoholic fatty liver disease using precision-cut liver slices

HIGHLIGHTS

  • who: Grietje H. Prins et al. from the Department of Pharmaceutical Technology and Biopharmacy, University of Groningen, Department of Pharmacology, Faculty of Pharmacy, Mahidol University, Bangkok, Thailand have published the paper: A Pathophysiological Model of Non-Alcoholic Fatty Liver Disease Using Precision-Cut Liver Slices, in the Journal: (JOURNAL)
  • what: The aim of this study was to induce liver steatosis in PCLSs, by using culture conditions that reflect metabolic syndrome.
  • how: The concentration of palmitic acid in this model might have been too low to cause mitochondrial dysfunction and was used for cellular . . .

     

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