A pendulum of induction between the epiblast and extra-embryonic endoderm supports post-implantation progression

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  • who: KEY WORDS Blastoids and collaborators from the In certain species, extrinsic positional cues create a pre-pattern for development, e_g through the local deposition of maternal RNA on one side of a Drosophila eggHowever, mammalian development appears to rather favor decentralized and regulative principles, termed self-organizing, that prevail over more deterministic , MERLN Institute for Technology-inspired Regenerative Medicine, Maastricht University, Universiteitssingel, ER Maastricht, Netherlands. Institute of Molecular Biotechnology of the Austrian Academy of Sciences, Vienna Biocenter, Dr. Bohr-Gasse, Vienna, Austria. Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW) and University Medical Center . . .

     

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