HIGHLIGHTS
- who: Elisabeth Simboeck from the (UNIVERSITY) have published the research work: A Phosphorylation Switch Regulates the Transcriptional Activation of Cell Cycle Regulator p21 by Histone Deacetylase Inhibitors*, in the Journal: (JOURNAL) of December/24,/2010
- what: Activation of p21 Expression by HDAC Inhibition Requires a Second Signal-In this study the authors intended to analyze the molecular mechanisms regulating the activation of the p21 gene in response to HDAC inhibitor treatment. The authors show here that the nucleosomal response is not only required for RNA_polymerase II recruitment to the p21 promoter but also important for . . .
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