A physiologically-based pharmacokinetic framework for prediction of drug exposure in malnourished children

HIGHLIGHTS

• who: Erik Sjögren et al. from the Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Oxford , LG, UK have published the research: A Physiologically-Based Pharmacokinetic Framework for Prediction of Drug Exposure in Malnourished Children, in the Journal: Pharmaceutics 2021, 13, 204. of /2021/
• what: A cefoxitin PBPK model was developed to serve the purpose of this study. In essence, the model structure and parametrization, i.e., the system, of a PBPK model aims to describe the organism.

SUMMARY

Uncertainties in how and to what extent . . .

 



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