A pipeline for phasing and genotype imputation on mixed human data (parents-offspring trios and unrelated subjects) by reviewing current methods and software

HIGHLIGHTS

  • who: Giulia Nicole Baldrighi et al. from the Department of Brain and Behavioral Sciences, University of Pavia, Pavia, Italy have published the Article: A Pipeline for Phasing and Genotype Imputation on Mixed Human Data (Parents-Offspring Trios and Unrelated Subjects) by Reviewing Current Methods and Software, in the Journal: Life 2022, 12, x FOR PEER REVIEW of 30/09/2022
  • what: In this approach, the unobserved genotypes are considered as random variables and their conditional distribution is evaluated using the observed genotypes and the reconstructed haplotypes. FastPHASE can be a good alternative for mixed data . . .

     

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