A plausible mechanism for the iridium-catalyzed hydrogenation of a bulky n-aryl imine in the (s)-metolachlor process

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  • who: Amanda L. Kwan and Robert H. Morris from the Department of Chemistry, University of Toronto, Toronto, ON M S , Canada have published the paper: A Plausible Mechanism for the Iridium-Catalyzed Hydrogenation of a Bulky N-Aryl Imine in the (S)-Metolachlor Process, in the Journal: Molecules 2022, 27, x FOR PEER REVIEW of /2022/
  • what: The authors propose a plausible proton-first outer-sphere mechanism based on density functional theory calculations that is consistent with the experimentally observed activity and the enantioselectivity of the industrial Key findings include transition states involving acetate-assisted . . .

     

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