A polygenic risk score for nasopharyngeal carcinoma shows potential for risk stratification and personalized screening

HIGHLIGHTS

• who: Yong-Qiao He from the The Institutional Review Board of Sun Yat-Sen University Cancer Center approved this studyInformed consent was obtained from all study participants. Study design and participants. The Chinese Nasopharyngeal Carcinoma Collaboration study (ChiCTR1900027868) includes , incident NPC cases and , hospital- and population-based non-NPC controls from regions with different NPC incidence rates in China. For the PRS construction, GWAS populations were included from regions in southern China with the highest NPC incidence, including the EPI-, sample (, cases and , controls)41, NPCGEE sample (, cases and , controls)43, SYSUNPC sample (, cases and , have published . . .
  

   

  

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