HIGHLIGHTS
- who: Szilvia Du00e9ri et al. from the Department of Pharmacology and Pharmacotherapy, University of Szeged, Szeged, Hungary Department of Medicine, Montreal Heart Institute, Universitu00e9 de Montru00e9al, Montru00e9al, QC H T , Canada have published the research: A Possible Explanation for the Low Penetrance of Pathogenic KCNE1 Variants in Long QT Syndrome Type 5, in the Journal: Pharmaceuticals 2022, 1550 of /2022/
- what: The authors demonstrate that KCNE3 a candidate regulatory subunit of IKs channels minimizes the inhibitory effects of LQT5 KCNE1 variants on IKs amplitudes while current deactivation is accelerated. The authors show that KCNE3 accomplishes . . .
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