A pro b cell population forms the apex of the leukemic hierarchy in hoxa9/meis1-dependent aml

HIGHLIGHTS

  • who: Anna Lieske from the (UNIVERSITY) have published the article: A pro B cell population forms the apex of the leukemic hierarchy in Hoxa9/Meis1-dependent AML, in the Journal: (JOURNAL) of 14/Dec/2022
  • what: Gene expression profiling identified the upregulation of lymphoid driver genes in the Lym+ LSC compartment To uncover the molecular mechanisms governing the plasticity and self-renewal potential of H9M LSC, the authors aimed to compare the global gene_expression profiles of sorted Lym+ and Lin- competent cells derived from three independent secondary recipients, each.
  • how: For this analysis . . .

     

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