A proof-of-concept inhibitor of endothelial lipase suppresses triple-negative breast cancer cells by hijacking the mitochondrial function

HIGHLIGHTS

• who: Rongze Yang and colleagues from the University of Maryland School of Medicine, Baltimore, MD, USA have published the paper: A Proof-of-Concept Inhibitor of Endothelial Lipase Suppresses Triple-Negative Breast Cancer Cells by Hijacking the Mitochondrial Function, in the Journal: (JOURNAL)
• what: The authors report that the expression of is associated with long non-coding RNA DANCR and positively correlates with gene signatures of metabolism-oxidative phosphorylation (OXPHOS). Treatment with cynaroside inhibited the phenotype of cells which severely impaired Taken together the study provides mechanistic insights into the modulation of metabolism in and . . .
  

   

  

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