A proposed novel genetic and epigenetic effects of betulinic acid against breast cancer cells: in silico and in vitro study

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  • who: Esraa El-Wakeel and collaborators from the Pharos University have published the research work: A proposed novel genetic and epigenetic effects of Betulinic acid against breast cancer cells: in silico and in vitro study, in the Journal: (JOURNAL)
  • what: On the cellular level, the study showed that BA exhibited a concentration-dependent reduction in cell viability accompanied by morphological changes in both MCF-7 and MDA-MB-231 cells, however, the ER (+) MCF-7 cells were more sensitive as evidenced by the 5 folds higher IC50 value of BA in MDA-MB-231 (100 . . .

     

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