A proteomic approach for the identification of cell-surface proteins shed by metalloproteases*

HIGHLIGHTS

  • who: Lin Guo from the Immunex Corporation have published the Article: A Proteomic Approach for the Identification of Cell-surface Proteins Shed by Metalloproteases*, in the Journal: (JOURNAL) of September/26,/2001
  • what: Except for saposin and tubulin, the proteins that were identified from the 2D-PAGE experiment are type 1 transmembrane_proteins , thus indicating that the lectin-affinity step was reasonably effective in eliminating cytoplasmic proteins. Identification of Metalloprotease-shed Proteins in Endothelial Cells-To determine whether this approach can be used to identify proteins shed by other cell types, the authors carried out a . . .

     

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