A qbd approach to design and to optimize the self-emulsifying resveratrol-phospholipid complex to enhance drug bioavailability through lymphatic transport

HIGHLIGHTS

  • who: Syed Abul Layes Gausuzzaman and collaborators from the Department of Pharmaceutical Sciences, North South University, Dhaka, Bangladesh have published the article: A QbD Approach to Design and to Optimize the Self-Emulsifying Resveratrol-Phospholipid Complex to Enhance Drug Bioavailability through Lymphatic Transport, in the Journal: (JOURNAL)
  • what: This approach observed minor benefits; instead, several toxicities were reported due to high doses during the clinical studies . Bypassing fast-pass metabolism and enterohepatic recirculation should be the main objectives to enhance the bioavailability of resveratrol, which was absent in those studies. By complexing resveratrol with phospholipid . . .

     

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