A radiogenomics biomarker based on immunological heterogeneity for non-invasive prognosis of renal clear cell carcinoma

HIGHLIGHTS

SUMMARY

    Radiogenomics combines gene_expression information with medical imaging features, thus enabling an in-depth understanding of tumor biology and capture of internal tumor heterogeneity information. Radiogenomics has the potential to become a promising noninvasive diagnostic method that can reflect gene_expression information. The immune-related gene_expression risk score was calculated and predicted using the radiogenomics approach to build molecular markers for the non-invasive prognosis evaluation of ccRCC. GSEA was conducted to normalize the gene_expression profile and to excavate GO and KEGG pathways. acquired from The selected optimal features were linearly combined with pass-through coefficients . . .

     

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