A raf-independent epidermal growth factor receptor autocrine loop is necessary for ras transformation of rat intestinal epithelial cells*

HIGHLIGHTS

• who: Lisa M. Gangarosa from the (UNIVERSITY) have published the research: A Raf-independent Epidermal Growth Factor Receptor Autocrine Loop Is Necessary for Ras Transformation of Rat Intestinal Epithelial Cells*, in the Journal: (JOURNAL) of November/12,/1996
• what: The authors have evaluated the role of EGF receptor (EGFR) ligands in mediating Ras transformation of RIE-1 cells.
• how: Inasmuch as reliable protein assays are not available for AR and HB-EGF the authors examined expression of mammalian EGFR ligands by Northern blot analysis.
• future: Future studies will address whether overexpression . . .
  

   

  

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