A rapid and sensitive liquid chromatography-tandem mass spectrometry bioanalytical method for the quantification of encorafenib and binimetinib as a first-line treatment for advanced (unresectable or metastatic) melanoma—application to a pharmacokinetic study

HIGHLIGHTS

• who: Mohamed M. Hefnawy and collaborators from the Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia have published the research: A Rapid and Sensitive Liquid Chromatography-Tandem Mass Spectrometry Bioanalytical Method for the Quantification of Encorafenib and Binimetinib as a First-Line Treatment for Advanced (Unresectable or Metastatic) Melanomau2014Application to a Pharmacokinetic Study, in the Journal: Molecules 2023, 79 of /2023/
• what: In this study and LC-MS/MS for simultaneous quantification of ENF and BNB in rat plasma was developed and validated. was performed on an Agilent Eclipse plus . . .
  

   

  

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