A realistic morpho-anatomical connection strategy for modelling full-scale point-neuron microcircuits

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SUMMARY

    The scaffolding of the neurons in the simulation volume was performed with the BSB (Brain Scaffold Builder) framework (https://​github.​com/​dbbs-​lab/​bsb)23 Since the present method is based on cell positions and on the relative distances between CA1 neurons and targeting subregions (CA3 and Subiculum), the authors refer to this approach as "Positional-Morpho-Anatomical" modeling (PMA). With this aim, point-like neurons, usually modelled as integrate-and-fire40 or Izhikevich ­models41, can be adopted to significantly reduce the com- | Vol:(1234567890) 12:13864 | | 12:13864 | 3 Vol.:(0123456789) Placement class . . .

     

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