A recombinant adenovirus vector containing the synnotch receptor gene for the treatment of triple-negative breast cancer

HIGHLIGHTS

• who: Ruhan A from the IRCCS, Italy Virginia Commonwealth University have published the Article: A recombinant adenovirus vector containing the synNotch receptor gene for the treatment of triple-negative breast cancer, in the Journal: (JOURNAL)
• what: The authors explored the feasibility of using AdCD44-N-HIF3a4 to treat TNBC by in_vitro and in_vivo experiments using MDA-MB-231 a human TNBC cells and compared it`s in_vivo anti-tumor activities with other adenovirus vectors, Ad-SOCS3 and Ad-p53 .
• how: As for the control breast cancer cell line the authors employed MCF-7 . . .
  

   

  

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