A residue quartet in the extracellular domain of the prolactin receptor selectively controls mitogen-activated protein kinase signaling*

HIGHLIGHTS

• who: Chi Zhang from the (UNIVERSITY) have published the article: A Residue Quartet in the Extracellular Domain of the Prolactin Receptor Selectively Controls Mitogen-activated Protein Kinase Signaling*, in the Journal: (JOURNAL) of January/21,/2015
• what: This was further confirmed by the experiments described below. The authors aimed to further investigate the importance of the residue located at position 170, Leu in the hPRLR versus Phe in the rPRLR. Because the regions and residues involved in both receptors are distinct, the authors aimed to understand the structural mechanisms involved in the PRLR.
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