A review of novel non-nucleoside anti-hbv agents and their mechanism of action

HIGHLIGHTS

• who: Yubin Li from the College of Science, Guangdong Ocean University, Zhanjiang, PRChina have published the paper: A Review of Novel Non-Nucleoside Anti-HBV Agents and Their Mechanism of Action, in the Journal: (JOURNAL)
• how: The luciferase reporter assay results showed that HE-145 inhibited selectively core promoter (CP) and surface antigen promoter II (SPII) but had no effect on X gene promoter (Xp) and surface antigen promoter I (SPI). The results showed that some of the analogues displayed inhibiting not only HBsAg and HBeAg secretion but also HBV DNA replication compared with 3TC . . .
  

   

  

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