A robust method for collider bias correction in conditional genome-wide association studies

HIGHLIGHTS

• who: Osama Mahmoud from the University of Bristol, Bristol, UK have published the Article: A robust method for collider bias correction in conditional genome-wide association studies, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
• what: This approach, implemented in the mtCOJO software, presumes a causal effect of I on P and the availability of unconditional G → P effects, but is not applicable to case-only studies of disease progression. The authors propose an alternative method, referred to as ‘SlopeHunter', for adjustment of collider bias in GWAS of conditional analyses (including index event bias in progression . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or E-mail:

  If you don't have an account, you can create one here.