A robust reprogramming strategy for generating hepatocyte-like cells usable in pharmaco-toxicological studies

HIGHLIGHTS

  • who: Guillem Garcia-Llorens from the (UNIVERSITY) have published the paper: A robust reprogramming strategy for generating hepatocyte-like cells usable in pharmaco-toxicological studies, in the Journal: (JOURNAL)
  • what: Although HLC do not yet display a fully mature phenotype, they outperform many other liver cell models and the degree of differentiation achieved is generally sufficient for most study goals.
  • how: Statistical analysis was carried out in MATLAB 2021a (Mathworks Inc []. The authors evaluated intra-clonal variability of the cell pharmaco-toxicological system model by RNAseq of P u00ad Dlow high low and . . .

     

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