A role for glutamate transporters in the regulation of insulin secretion

HIGHLIGHTS

• who: Runhild Gammelsaeter et al. from the Department of Anatomy and CMBN, University of Oslo, Oslo, Norway, Institut de Pharmacologie Moléculaire et Cellulaire, Université de Nice, Nice, France have published the article: A Role for Glutamate Transporters in the Regulation of Insulin Secretion, in the Journal: (JOURNAL) of August/11,/2011
• what: By immunogold cytochemistry the authors show that insulin containing secretory granules express VGLUT3. EAAT2 keeps the glutamate levels in the insulin granules low Based on the data above, the authors propose that there is a flux of glutamate through the secretory granules . . .
  

   

  

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