HIGHLIGHTS
- who: Asymmetric Catalysis and colleagues from the The GlaxoSmithKline Carbon Neutral Laboratories for Sustainable Chemistry, University of Nottingham, Jubilee Campus, Triumph Road, Nottingham, TU, United have published the research work: A Scalable Synthesis of Chiral Himbert Diene Ligands for Asymmetric Catalysis, in the Journal: (JOURNAL)
- what: The authors show that intramolecular cycloaddition of a simply attained chiral allenecarboxanilide readily affords pseudoenantiomeric bicycl octa-2 5dienes containing an alkenyl bromide which can be readily functionalized to give diverse chiral diene ligands.
- how: The authors therefore decided to incorporate a chiral auxiliary into the cycloaddition . . .
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